Carbidopa and Levodopa
BRAND: Atamet, Sinemet, Sinemet CR
Carbidopa and levodopa is a medication used to treat Parkinson's disease. Levodopa is turned into dopamine in the body. When added to levodopa, carbidopa delays the conversion of levodopa into dopamine until it reaches the brain, preventing or diminishing some of the side effects that often accompany levodopa therapy. Carbidopa also reduces the amount of levodopa needed by about 75%.
Carbidopa and levodopa is used to treat the stiffness, tremors, spasms, and poor muscle control associated with Parkinson's disease. This medication is also used to treat the same muscular conditions when they are caused by carbon monoxide and/or manganese intoxication.
Do Not Take Carbidopa and Levodopa If..
Donot take this medication if you have:
You may not be able to take carbidopa and levodopa, or you may need a lower dose or special monitoring during treatment if you have any of the conditions listed above.
FDA classifies Carbidopa and levodopa in the pregnancy category C. This means that it is not known whether carbidopa and levodopa will harm an unborn baby. Do not take carbidopa and levodopa without first talking to your doctor if you are pregnant.
It is also not known whether carbidopa and levodopa will harm a nursing infant. Do not take carbidopa and levodopa without first talking to your doctor if you are breast-feeding a baby.
If You overdose
Seek emergency medical attention immediately
Symptoms of a carbidopa and levodopa overdose include muscle spasms or weakness, spasms of the eyelid, nausea, vomiting, diarrhea, irregular heartbeat, confusion, agitation, hallucinations, and unconsciousness.
Avoid The Following While Taking Carbidopa and Levodopa
Use caution when driving, operating machinery, or performing other hazardous activities. Carbidopa and levodopa may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities.
Do not change the amount of protein in your diet without first talking to your doctor. Protein may reduce the amount of carbidopa and levodopa that gets absorbed into your body.
Side Effects of Carbidopa and Levodopa
If you experience any of the following serious side effects, stop taking carbidopa and levodopa and seek emergency medical attention:
Other Side Effects
The following side reactions are less serious and are more likely to occur. Continue to take carbidopa and levodopa and talk to your doctor if you experience:
Do not take carbidopa and levodopa if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate) in the past 14 days.
If you are already taking levodopa (Larodopa, Dopar) you will have to stop taking it at least 12 hours before you take your first dose of carbidopa and levodopa.
Before taking carbidopa and levodopa, tell your doctor if you are taking any of the following medicines:
You may not be able to take carbidopa and levodopa, or you may require a dosage adjustment or special monitoring during treatment if you are taking any of the medicines listed above.
Levodopa may interfere with urine tests for sugar and ketones. If you are diabetic and notice changes in your urine test results, talk to your doctor before making any changes in your diabetes medication.
Drugs other than those listed here may also interact with carbidopa and levodopa. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.
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