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 Bioterrorism  Holistic-online.com

Critical biological agents that may be used in Bioterrorism

Category A

These include organisms that pose a risk to national security. They
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can be easily disseminated or transmitted person-to-person;

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cause high mortality, with potential for major public health impact;

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might cause public panic and social disruption; and

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require special action for public health preparedness

Category A agents include

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variola major (smallpox);

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Bacillus anthracis (anthrax);

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Yersinia pestis (plague);

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Clostridium botulinum toxin (botulism);

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Francisella tularensis (tularaemia);

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filoviruses,
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Ebola hemorrhagic fever,

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Marburg hemorrhagic fever; and

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arenaviruses,
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Lassa (Lassa fever),

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Junin (Argentine hemorrhagic fever) and related viruses.

Category B

These agents
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are moderately easy to disseminate;

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cause moderate morbidity and low mortality; and

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require enhancements to diagnostic capacity and enhanced disease surveillance.

Category B agents include
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Coxiella burnetti (Q fever);

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Brucella species (brucellosis);

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Burkholderia mallei (glanders);

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alphaviruses,
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Venezuelan encephalomyelitis,

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eastern and western equine encephalomyelitis;

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ricin toxin from Ricinus communis (castor beans);

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epsilon toxin of Clostridium perfringens; and

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Staphylococcus enterotoxin B.

A subset of List B agents includes pathogens that are food- or waterborne.
These pathogens include but are not limited to
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Salmonella species,

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Shigella dysenteriae,

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Escherichia coli O157:H7,

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Vibrio cholerae, and

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Cryptosporidium parvum.

Category C

These agents include emerging pathogens that could be engineered for mass dissemination in the future because of
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availability;

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ease of production and dissemination; and

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potential for high morbidity and mortality and major health impact.

Category C agents include
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Nipah virus,

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hantaviruses,

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tickborne hemorrhagic fever viruses,

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tickborne encephalitis viruses,

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yellow fever, and

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multidrug-resistant tuberculosis.

Management of category C agents requires ongoing research to improve disease detection, diagnosis, treatment, and prevention.

Source: "Biological and Chemical Terrorism: Strategic Plan for Preparedness and Response: Recommendations of the CDC Strategic Planning Workgroup," April 21, 2000 / 49(RR04);1-14, Centers for Disease Control, USA.

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